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Targets Recommended: Carbonic Anhydrase

3

抑制剂 & 化合物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T61745 hCAI/II-IN-6

Carbonic Anhydrase Metabolism
hCAI/II-IN-6 是一种具有选择性和口服活性的human carbonic anhydrase(CA) 抑制剂。hCAI/II-IN-6对 hCA I,hCA II,hCA VII 和 hCA XII 有抑制作用,Ki 值分别为 220,4.9,6.5 和 >50000 nM。hCAI/II-IN-6 在体内显示抗惊厥活性。hCAI/II-IN-6 可以用于研究癫痫。
T78729 hCAIX/VII-IN-1

Carbonic Anhydrase Metabolism
hCAIX/VII-IN-1是一种选择性hCA VII/IX抑制剂,对hCAⅠ、hCAⅡ、hCAⅣ、hCAⅦ和hCAⅨ的Ki值分别为336.2 nM、185.8 nM、1055 nM、35.6 nM和28.0 nM。hCAIX/VII-IN-1主要用于癌症和神经疾病的研究。
T35876 Chlorthalidone Impurity G

Chlorthalidone impurity G is a potential impurity found in commercial preparations of chlorthalidone that has moderate antihypertensive effects. Chlorthalidone is a thiazide-like diuretic that inhibits the Na+/Cl- cotransporter in the distal convoluted tubule of the kidney, which prevents reabsorption of sodium and chloride leading to a reduction in plasma volume and cardiac output. It also inhibits carbonic anhydrase (CA), including the isoforms CAVB, VII, IX, XII, and XIII (Kis = 2.8-23 nM) an...

化合物

hCAI/II-IN-6
Cat.No: T61745
Synonym:
Target: Carbonic Anhydrase
hCAIX/VII-IN-1
Cat.No: T78729
Synonym:
Target: Carbonic Anhydrase
Chlorthalidone Impurity G
Cat.No: T35876
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-02277 Carbonic Anhydrase 7 Protein, Human, Recombinant (His)

CAVII,carbonic anhydrase VII<...

Human E. coli
Carbonic anhydrase 7, also known as carbonate dehydratase VII, carbonic anhydrase VII, CA-VII and CA7, is a cytoplasm protein which belongs to thealpha-carbonic anhydrase family. Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, ...

重组蛋白

Carbonic Anhydrase 7 Protein, Human, Recombinant (His)
Cat.No: TMPY-02277
Species: Human
Expression System: E. coli
TargetMol Loading
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